Scholarly Commons @Augusta University
Scholarly Commons is Augusta University's institutional repository and aims to preserve and distribute scholarly works and historical documents generated by the University and its legacy institutions. Scholarly Commons is managed by the Augusta University Libraries. For more information about the repository, please see the Scholarly Commons Guide or contact Jennifer Davis, Scholarship and Data Librarian, at jdavis14@augusta.edu.
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- Materials created by University Affiliates related to COVID-19
- Manuscripts from AU faculty who received awards to cover open access processing charges (APCs)
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Recent Submissions
A Multidimensional Research Productivity Dataset of 21st Century Nobel Laureates in Physiology or Medicine
(Augusta University, 2024-11) Burnett, Wendy Janda; Balas, E. Andrew
The study of research leading to significant discoveries and best practices of elite scientists is a major opportunity for advancing public health and developing effective research. This dataset was created by conducting an automated and manual search of the internet using a large variety of publicly available sources including but not limited to the nobelprize.org website, PubMed, university web and profile pages, the United States Patent and Trademark Office (USPTO), the NIH RePORTER database, Retraction Watch, and Clarivate. Each download was meticulously matched to the Laureate by cross-checking the above sources, collaborators, content, and production dates. Our unique dataset comprises 12,943 publications, 940 US patents, 17 retractions, and 2,093 peer-reviewed NIH awards produced by 21st-century Nobel laureates in Physiology or Medicine (2000-2023) prior to winning the Nobel Prize. The data provide multiple descriptors (i.e., number of publications, number and amount of NIH awards, number of patents), which can be used by the scientific community for practical purposes such as productivity desiderata for researchers, grant program design, and research policy development.
Arsenal: Volume 7, Issue 3 (Fall 2024)
(Augusta University Libraries, 2024-11) Le, Kaitlyn T.; Adu, Zaneta; Allen, Tate; Johnson, Trinity
How Playing with Virtual Dirt Got Me a Biology Degree
(Augusta University Libraries, 2024-11) Le, Kaitlyn T.
Last summer I spent 20 hours a week crafting in the void that is virtual pottery for research. I signed up for this project merely because it sounded like the most fun. I did not foresee that the skills I learned would aid my journey in getting my biology degree. The privilege of participating in undergraduate research at Augusta University has completely rewired the way I think innovatively, ask questions, and build relationships. Which have yielded skills and resources that contributed to my academic success in getting my degree, and also developed me as a young adult in the real world.
The Link between Racial, Ethnic, and Socioeconomic Disparities, Maternal Mental Health, and Birth Outcomes
(Augusta University Libraries, 2024-11) Adu, Zaneta
This study sought to understand the link between maternal mental health and birth outcomes, exacerbated by ethnic and socioeconomic disparities among women in the U.S. It was hypothesized that minorities experienced adverse birth outcomes, specifically preterm birth and low birth weight, due to a higher risk for mental health disorders. The study used a data set consisting of 38 participants, two of whom had twins, who utilized a pregnancy and postpartum assessment application called vidaRPM, to produce 41 sets of data. Data from this application were collected and examined for potential relationships between mood alerts (moments of concern for a participant’s mental health) and preterm birth, low birth weight, and high blood pressure. The results did not indicate any significant relationships between mood alerts and any of the physical health indicators analyzed in this project, suggesting that there are more aspects to consider than just ethnicity when conducting a study of this magnitude.
Kynurenine’s Effect on the Different Stages of Osteoblastic Differentiation
(Augusta University Libraries, 2024-11) Allen, Tate
This study focuses on the dynamics of age-related changes in osteoblasts’ matrix production, with a specific focus on the involvement of the aryl hydrocarbon receptor (AhR). The AhR is activated by kynurenine, a metabolite of the amino acid tryptophan that tends to increase with age. Kynurenine has been known to impair osteoblasts’ bone formation ability, however, the point at which this occurs is unknown. The study utilizes a 21-day differentiation process of mesenchymal stem cells. “Window experiments” that vary the intervals of kynurenine treatment to explore its impact at different stages of osteoblast development were utilized. The experimental setup involves four distinct conditions: a control group with a vehicle, a group treated with kynurenine, a group with an AhR antagonist (BAY), and a group treated with both kynurenine and BAY. The AhR antagonist, specifically BAY2416964, serves to investigate whether any observed effects of kynurenine are mediated through AhR signaling. Results, analyzed through alizarin red staining, demonstrate a notable negative impact of kynurenine on matrix production, particularly in the middle stages of osteoblast differentiation. The study further employs crystal violet staining to confirm the presence of cells in the experimental wells, providing assurance of the reliability of the alizarin staining procedure. Importantly, this staining procedure also suggests that the effects of kynurenine on mineralized matrix production are largely independent of any potential impacts on cell viability.