DNA Sequencing of Extensive Odontogenic Keratocysts with Possible Therapeutic Implications

Abstract

Purpose of this research is: to perform DNA sequencing on a group of previously diagnosed OKC of the jaws which demonstrated clinical aggressive behavior; Compare the genetic profile of the aggressive OKC cases with the genetic profile of a similar number of OKC cases which did not demonstrate aggressive clinical behavior; Evaluate the possibility of therapeutic implications of genetic mutations noted in OKCs