ATAD3A plays an oncogenic role in head and neck cancer

Abstract

With approximately 500,000 new cases diagnosed each year, head and neck squamous cell carcinomas (HNSCC) remain one of the leading causes of cancer related deaths. Thus, there is great interest to identify novel therapeutic targets against HNSCC. In this project, we aim to gain a deeper appreciation of ATAD3A, the ATPase family AAA-domain containing protein3A, and its oncogenic role in HNSCC, as well as its potential as a target in future patient therapies.